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. 2021 May 12;22(10):5108. doi: 10.3390/ijms22105108

Table 1.

Km, Vmax and AC50 values of the chosen phenolic acids on thyroid peroxidase (TPO) activity, n = 9.

Compound Km [mM] Vmax [ΔAU/min] AC50 [mM]
Guaiacol 1 0.06 ± 0.003 120.5 ± 5.38 d -
trans–cinnamic acid - 128.2 ± 4.12 c 0.10 ± 0.005 c
Syringic acid - 243.9 ± 9.54 b 0.69 ± 0.034 a
Ferulic acid - 294.1 ± 9.12 a 0.39 ± 0.019 b

1 TPO substrate. Values are expressed as the mean ± SD; means with different letter superscripts (a–d) in the columns are significantly different (α = 0.05).