Table 1.
Mortality and change in body weight in the mice injected with various doses of free TQ or Lip-TQ. The data are represented as the means ± SD of three independent experiments.
| Group | Mortality | Body Weight | ||
|---|---|---|---|---|
| Day 1 | Day 5 | Day 11 | ||
| Vehicle control | 0/8 | 28 ± 2.4 | 28.8 ± 2.2 | 29.2 ± 2.1 |
| Sham liposomes | 0/8 | 27.4 ± 3.0 | 27.7 ± 3.1 | 28.2 ± 3.3 |
| Free TQ—1 mg/kg | 0/8 | 29.6 ± 1.8 | 29.6 ± 2.2 | 30 ± 2.0 |
| Free TQ—10 mg/kg | 0/8 | 28.8 ± 2.5 | 28.7 ± 2.4 | 28 ± 3.4 |
| Free TQ—20 mg/kg | 0/8 | 28.6 ± 2.4 | 28.4 ± 3.6 | 27.8 ± 3.6 |
| Free TQ—40 mg/kg | 0/8 | 28.2 ± 2.2 | 26.5 ± 3.4 | 26.4 ± 3.1 |
| Lip-TQ—1 mg/kg | 0/8 | 26.6 ± 1.7 | 29.2 ± 1.8 | 27.7 ± 1.5 |
| Lip-TQ—10 mg/kg | 0/8 | 28.5 ± 3.8 | 28.6 ± 2.7 | 27.6 ± 2.5 |
| Lip-TQ—20 mg/kg | 0/8 | 29.4 ± 2.6 | 29 ± 3.2 | 28.2 ± 4.0 |
| Lip-TQ—40 mg/kg | 0/8 | 29 ± 3.5 | 28.4 ± 3.0 | 27.8 ± 3.8 |