Table 6.
Top important variables for each of the targets. The variables were aggregated by the median value of the permutation importance per target (600 runs each). The permutation importance is divided by the respective Matthews correlation coefficient (MCC) value from Table 5 and calculated as the % of weight respective to the MCC, i.e., contribution to MCC. For each target, only several variables returned an aggregated median above 1%. hsCRP: high-sensitivity C-reactive protein and t0: baseline.
| Variable | LOAC | FENO | FEV1 | MEF50 |
|---|---|---|---|---|
| Seasonal allergens (SPT) | 1.1% | |||
| Asthma severity (t0) | 47.0% | |||
| hsCRP | 1.2% | |||
| IgE total | 1.5% | 3.2% | ||
| FENO (t0) | 12.8% | |||
| FEV1 (t0) | 14.8% | 1.8% | ||
| MEF50 (t0) | 8.2% | 30.3% |