Scheme 13.
Reagents and conditions: (a) TEA, TBDMSOTf; (b) N-(Fmoc-amino)ethylmaleimide; (c) Boc2O, NEM; (d) 20% piperidine, DMF; (e) Pd(PPh3)4, NEM, AcOH; (f) BocY(NO2)E(tBu)K(Boc)FR(Pmc)---R(Pmc)GK(Boc)K((Boc)-Abz)G-OH, TBTU/NEM.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.