Table 1.

The IC₅₀ values (µM) of the tested molecules determined in the epimastigotes of T. cruzi (CLB strain).

Compound	IC50 (µM) ƚ
MM3	4.52 ± 1.43
MM4	5.08 ± 0.62
MM5	129.91 ± 34.66
EH123	198.78 ± 49.93
Obatoclax	3.46 ± 0.96
Synthetic prodigiosin	0.46 ± 0.03
Natural prodigiosin	0.54 ± 0.25
Benznidazole	18.96 ± 7.07

MM3, MM4, MM5, and EH123 are all tambjamines. ƚ Results are expressed as the mean IC₅₀ value for each compound (± standard deviation) using data obtained in triplicate runs from three independent experiments. The IC₅₀ value is the concentration that causes 50% of growth inhibition. This value was calculated using the GraphPad Prism software.