Table 1.

Clustering viruses by antibody recognition patterns. (A) Data are from a neutralization experiment by Moore et al. [38], from which ID₅₀ scores were recorded. Viruses and clades/subtypes are listed in the first two columns, and sera are listed as headers of additional columns. The year and origin of virus isolation is defined in the name (TH = Thailand, UG = Uganda, RW = Rwanda, BR = Brazil). Clade/subtype “E” is now recognized as a circulating recombinant form AE [40]. Each entry is ID₅₀, with ‘0‘ representing no neutralization, and ‘256’ representing an ID₅₀ greater than 128. (B) Values from Table 1A were ranked from 1 to 5, and ranks were color-coded using Microsoft Excel software (Microsoft Corporation, Remond, Washington, USA). Viruses were grouped based on similar antibody reactivity patterns using Dmax = 20 (viruses with summed differences ≤ Dmax compared to a leader were assigned to the same group). There were seven groups (separated by thick black lines) with respective leaders indicated at the top of each group in bold type.

A. Original Data
VIRUSES	VIRUS CLADE	ID50 WITH HUMAN SERUM SAMPLES:
Virus		92UG029	92UG031	92UG037	92RW009	92RW008	92TH014	92TH 026	92BR 020	92BR 021	92BR 023	92BR025	92UG001	92UG005	92UG021	92UG046	92UG024	92TH006	92TH009	92TH022	92TH024	92TH023
_92ug029	A	0	256	0	0	32	256	256	0	0	64	256	256	256	64	32	256	128	0	256	32	256
_92ug031	A	16	16	128	8	64	8	16	0	0	32	8	16	128	16	0	0	8	32	64	8	0
_92ug037	A	0	32	128	8	256	0	0	0	0	128	64	0	32	0	0	0	0	64	64	0	0
_92rw009	A	0	32	64	8	256	16	0	0	0	32	64	0	64	0	0	0	0	32	32	8	0
_92rw008	A	0	128	128	128	32	0	8	0	0	128	32	128	128	128	128	0	0	0	8	0	0
_92th014	B	128	16	128	8	128	128	128	128	128	128	128	0	128	0	0	8	0	8	128	64	8
_92th026	B	0	0	0	0	32	8	0	0	0	0	0	8	256	0	0	0	0	0	8	0	0
_92br020	B	32	0	0	0	32	0	16	0	0	0	0	0	128	0	0	0	0	0	0	16	0
_92br021	B	0	0	0	0	32	0	8	16	8	8	0	0	128	0	0	0	0	8	0	8	0
_92br023	B	0	64	32	64	128	0	0	0	128	0	128	16	128	0	0	0	0	16	128	0	0
_92bf025	C	0	16	0	0	128	0	0	0	0	8	8	0	0	0	0	0	0	0	8	0	0
_92ug001	D	8	256	8	0	64	64	256	8	0	64	256	256	256	32	8	256	128	8	256	256	256
_92ug005	D	0	64	64	64	256	64	64	0	0	256	64	32	256	0	8	0	0	128	256	16	0
_92ug021	D	0	0	0	0	8	0	0	0	0	0	0	0	8	0	0	0	0	0	0	256	0
_92ug046	D	0	0	0	0	8	0	0	0	0	0	0	0	128	8	0	0	0	0	0	0	0
_92ug024	D	0	0	0	0	32	0	0	0	0	0	0	0	16	0	0	0	0	0	0	0	0
_92th006	“E”	0	8	128	128	32	128	16	64	0	0	128	0	32	128	128	64	128	32	0	0	128
_92th009	“E”	0	16	32	128	16	128	32	16	0	0	128	0	8	128	64	8	64	16	16	0	128
_92th022	“E”	0	128	128	128	32	128	64	128	0	0	128	8	128	128	128	64	128	32	0	0	128
_92th024	“E”	0	16	32	128	16	128	0	128	0	0	16	0	16	128	32	0	8	0	16	0	128
_92th023	“E”	0	8	64	128	32	128	0	16	0	0	16	0	8	128	128	8	16	8	0	0	128
B. Grouped viruses
VIRUSES		RANKED SCORES WITH HUMAN SERUM SAMPLES:
		92UG029	92UG031	92UG037	92RW009	92RW008	92TH014	92TH026	92BR020	92BR021	92BR023	92BR025	92UG001	92UG005	92UG021	92UG046	92UG024	92TH006	92TH009	92TH022	92TH024	92TH023
_92ug001	D	2	5	2	1	4	4	5	2	1	4	5	5	5	3	2	5	4	2	5	5	5
_92ug029	A	1	5	1	1	3	5	5	1	1	4	5	5	5	4	3	5	4	1	5	3	5
_92ug024	D	1	1	1	1	3	1	1	1	1	1	1	1	2	1	1	1	1	1	1	1	1
_92th026	B	1	1	1	1	3	2	1	1	1	1	1	2	5	1	1	1	1	1	2	1	1
_92br020	B	3	1	1	1	3	1	2	1	1	1	1	1	4	1	1	1	1	1	1	2	1
_92br021	B	1	1	1	1	3	1	2	2	2	2	1	1	4	1	1	1	1	2	1	2	1
_92br025	C	1	2	1	1	4	1	1	1	1	2	2	1	1	1	1	1	1	1	2	1	1
_92ug021	D	1	1	1	1	2	1	1	1	1	1	1	1	2	1	1	1	1	1	1	5	1
_92ug046	D	1	1	1	1	2	1	1	1	1	1	1	1	4	2	1	1	1	1	1	1	1
_92th022	“E”	1	4	4	4	3	4	4	4	1	1	4	2	4	4	4	4	4	3	1	1	4
_92th006	“E”	1	2	4	4	3	4	2	4	1	1	4	1	3	4	4	4	4	3	1	1	4
_92th009	“E”	1	2	3	4	2	4	3	2	1	1	4	1	2	4	4	2	4	2	2	1	4
_92th023	“E”	1	2	4	4	3	4	1	2	1	1	2	1	2	4	4	2	2	2	1	1	4
_92ug037	A	1	3	4	2	5	1	1	1	1	4	4	1	3	1	1	1	1	4	4	1	1
_92ug031	A	2	2	4	2	4	2	2	1	1	3	2	2	4	2	1	1	2	3	4	2	1
_92rw009	A	1	3	4	2	5	2	1	1	1	3	4	1	4	1	1	1	1	3	3	2	1
_92ug005	D	1	4	4	4	5	4	4	1	1	5	4	3	5	1	2	1	1	4	5	2	1
_92br023	B	1	4	3	4	4	1	1	1	4	1	4	2	4	1	1	1	1	2	4	1	1
_92th024	“E”	1	2	3	4	2	4	1	4	1	1	2	1	2	4	3	1	2	1	2	1	4
_92th014	B	4	2	4	2	4	4	4	4	4	4	4	1	4	1	1	2	1	2	4	4	2
_92rw008	A	1	4	4	4	3	1	2	1	1	4	3	4	4	4	4	1	1	1	2	1	1