Table 2.
Variables | CD11b | CD66b | CXCR2 | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Low | High | p-Value | Low | High | p-Value | Low | High | p-Value | ||||||||
N | % | N | % | N | % | N | % | N | % | N | % | |||||
Age (years) | ||||||||||||||||
<55 | 53 | 38.7 | 73 | 52.9 | 0.018 | 72 | 52.2 | 55 | 39.9 | 0.040 | 61 | 42.4 | 68 | 47.6 | 0.377 | |
≥55 | 84 | 61.3 | 65 | 47.1 | 66 | 47.8 | 83 | 60.1 | 83 | 57.6 | 75 | 52.5 | ||||
Tumor size | ||||||||||||||||
T1 | 56 | 40.9 | 71 | 51.5 | 0.079 | 70 | 50.7 | 57 | 41.3 | 0.116 | 68 | 47.2 | 64 | 44.8 | 0.675 | |
T2/T3/T4 | 81 | 59.1 | 67 | 48.6 | 68 | 49.3 | 81 | 58.7 | 76 | 52.8 | 79 | 55.2 | ||||
Nodal status | ||||||||||||||||
N− | 84 | 61.3 | 95 | 68.8 | 0.190 | 88 | 63.8 | 92 | 66.7 | 0.613 | 90 | 62.5 | 97 | 67.8 | 0.343 | |
N+ | 53 | 38.7 | 43 | 31.2 | 50 | 36.2 | 46 | 33.3 | 54 | 37.5 | 46 | 32.2 | ||||
Histological grade | ||||||||||||||||
1–2 | 48 | 35.8 | 14 | 10.2 | <0.001 | 47 | 34.8 | 14 | 10.2 | <0.001 | 49 | 34.8 | 16 | 11.3 | <0.001 | |
3 | 86 | 64.2 | 123 | 89.8 | 88 | 65.2 | 123 | 89.8 | 92 | 65.3 | 126 | 88.7 | ||||
Histology | ||||||||||||||||
Ductal | 109 | 79.6 | 118 | 87.4 | 0.082 | 109 | 79.6 | 120 | 88.2 | 0.051 | 111 | 78.2 | 124 | 87.3 | 0.041 | |
Other | 28 | 20.4 | 17 | 12.6 | 28 | 20.4 | 16 | 11.8 | 31 | 21.8 | 18 | 12.7 | ||||
Adjuvant chemotherapy | ||||||||||||||||
No | 40 | 29.4 | 26 | 18.8 | 0.041 | 25 | 18.3 | 42 | 30.4 | 0.019 | 38 | 26.6 | 32 | 22.4 | 0.409 | |
Yes | 96 | 70.6 | 112 | 81.2 | 112 | 81.8 | 96 | 69.6 | 105 | 73.4 | 111 | 77.6 | ||||
Basal-like phenotype | ||||||||||||||||
No | 55 | 40.4 | 41 | 29.9 | 0.069 | 46 | 33.8 | 52 | 37.7 | 0.505 | 56 | 39.4 | 45 | 31.5 | 0.160 | |
Yes (Basal) | 81 | 59.6 | 96 | 70.1 | 90 | 66.2 | 86 | 62.3 | 86 | 60.6 | 98 | 68.5 | ||||
Molecular apocrine phenotype | ||||||||||||||||
No | 61 | 48.4 | 91 | 68.4 | 0.001 | 71 | 55.9 | 83 | 61.5 | 0.359 | 66 | 50.0 | 93 | 66.4 | 0.006 | |
Yes (Molecular apocrine) | 65 | 51.6 | 42 | 31.6 | 56 | 44.1 | 52 | 38.5 | 66 | 50.0 | 47 | 33.6 |
Footnote: Basal-like phenotype was considered in the case of positive staining for cytokeratin 5/6 and/or EGFR (>10% of tumor cells stained in IHC); Molecular apocrine phenotype was defined in TNBC tumors that express both AR (androgen receptor) and FOXA1 (Forkhead box protein A1) biomarkers.