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The effect of fish-derived dietary supplements on abdominal fat and leptin expression in abdominal fat tissue of high-fat diet-fed mice. Mice were fed with the indicated nutritional supplement (A). Abdominal fat in grams normalized to total body weight was measured (B). Leptin expression levels in abdominal fat tissue were quantified using real-time PCR. A Mann–Whitney t-test was performed. * p < 0.05, ** p < 0.01, *** p < 0.001.
