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. 2021 May 12;21(10):3366. doi: 10.3390/s21103366

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Results for (a) GLUP, (b) VCA, (c) N-FINDR, and (d) SSM-S. The extracted endmembers are shown (left). The mean values of the endmembers are: 0.17, 0.39, 0.41, and 0.61 for Hb (in blue) and 0.16, 0.24, 0.24, and 0.48 for HbO $_{2}$ (in red), respectively for GLUP, VCA, N-FINDR, and SSM-S. The sO $_{2}$ maps estimated using the FCLS with the extracted endmembers and Equation (16) are highlighted (center). The relative deviation maps between these sO $_{2}$ maps and the Vevo LAZR map in Figure 12 are presented (right). The mean relative deviations for the whole image (black) and limited to the tumor (green) are given on the far right. The minimal relative deviations are circled in red. The image axes are in millimeters.