Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(a) Schematic structure of disulfide-containing linker and its reaction with thiols, like GSH to release payload. (b) Schematic representation of maytansinoid ADC linker highlighting the role of alpha-methyl groups (R1 to R4). (c) Linker structure of SAR-3419 containing the DM4 payload and the SPDB linker.
