Table 1.
Incident cases, deaths and DALYs of multiple myeloma in 2019, and percentage change of age-standardized rates by sex and GBD region
| Incidence | Deaths | DALYs | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Number of incident cases | Age standardized incidence rate (per 100,000 population) | Percentage change in rates(%), 1990–2019 | Number of deaths | Age standardized death rate (per 100,000 population) | Percentage change in rates(%), 1990–2019 | Number of DALYs*103 | Age standardized DALY rate (per 100,000 population) | Percentage change in rates(%), 1990–2019 | |
| Global | 155,688 (136585–172,577) | 1.92 (1.68–2.12) | 10.99(−5.11–21.64) | 113,474 (99527–121,735) | 1.42 (1.24–1.52) | 1.43(− 13.98–7.98) | 2497.2 (2190.5–2722.7) | 30.26 (26.58–32.9) | −0.85(− 17.48–6.66) |
| Sex | |||||||||
| Females | 71,171 (60343–80,140) | 1.62 (1.38–1.83) | 4.65(− 11.58–14.6) | 53,029 (45149–58,252) | 1.21 (1.03–1.33) | −3.82(− 19.80–2.84) | 1120.6 (967.7–1243.7) | 25.67 (22.15–22.48) | −6.11(− 23.87–1.17) |
| Males | 84,516 (70924–94,910) | 2.28 (1.91–2.56) | 16.03(− 1.45–29.18) | 60,445 (50723–67,056) | 1.68 (1.40–1.84) | 5.7(− 9.92–14.3) | 1376.6 (1150.6–1567.8) | 35.51 (29.77–40.03) | 3.4(− 14.14–13.72) |
| Socio-demographic index | |||||||||
| High SDI | 72,250 (62610–82,520) | 3.77 (3.29–4.33) | 16.66 (5.06–32.25) | 48,108 (41267–51,245) | 2.4 (2.1–2.59) | 2.29(− 3.93–11.12) | 901.2 (811.9–1007.5) | 49.3 (45.25–55.85) | −2.41(− 8.13–13.1) |
| High-middle SDI | 37,329 (30933–41,806) | 1.83 (1.52–2.05) | 21.54(− 1.95–36.12) | 27,224 (22937–29,555) | 1.34 (1.13–1.45) | 10.66(− 10.62–20.44) | 605.9 (506.6–659.7) | 29.77 (24.79–32.47) | 5.33(− 15.84–15.34) |
| Middle SDI | 25,294 (20919–28,629) | 1.01 (0.83–1.14) | 19.55(− 14.5–36.97) | 21,143 (17470–24,144) | 0.86 (0.71–0.99) | 11.68(− 21.22–27.39) | 134.7 (107.4–158.1) | 20.74 (16.96–23.57) | 10.48(− 24.71–27.2) |
| Low-middle SDI | 13,654 (11831–15,809) | 0.99 (0.86–1.15) | 20.83(− 10–38.57) | 12,040 (10183–14,016) | 0.89 (0.76–1.05) | 13.77(− 14.1–29.67) | 312.7 (267.2–366.6) | 21.75 (18.57–25.5) | 14.19(− 14.94–31.05) |
| Low SDI | 5148 (4101–5981) | 1 (0.8–1.16) | 3.18(− 22.53–22.54) | 4970 (3938–5768) | 1.01 (0.8–1.17) | 5.99(− 21.03–25.9) | 540.9 (442.1–614.1) | 24.16 (19.2–28.19) | 5.2(− 22.32–27.82) |
| Region | |||||||||
| Andean Latin America | 955 (747–1214) | 1.71 (1.34–2.18) | 16.08(− 25.14–55.8) | 788 (622–995) | 1.43 (1.13–1.8) | 3.46(− 31.28–38.21) | 18.9 (14.67–24.07) | 33.29 (25.84–42.26) | 1.6(− 34.2–38.53) |
| Australasia | 2658 (2101–3388) | 5.33 (4.21–6.8) | 25.1(− 0.82–60.03) | 1541 (1328–1736) | 2.97 (2.59–3.39) | 6.38(− 4.64–24.37) | 29.51 (26.16–34.07) | 61.23 (54.51–70.45) | 1.41(− 8.47–23.89) |
| Caribbean | 1686 (1401–1993) | 3.25 (2.7–3.84) | 27.38 (7.33–49.9) | 1224 (1022–1442) | 2.36 (1.97–2.79) | 14.95(− 1.89–34.35) | 28.86 (24.02–34.53) | 55.51 (46.25–66.5) | 16.62(− 0.97–38.02) |
| Central Asia | 608 (533–686) | 0.8 (0.7–0.89) | 33.1 (12.6–55.55) | 502 (441–564) | 0.69 (0.61–0.78) | 30.58 (11.09–53.2) | 14.33 (12.6–16.23) | 17.57 (15.43–19.77) | 32.24 (12.37–54.72) |
| Central Europe | 4550 (3599–5249) | 2.13 (1.69–2.46) | 37.47 (6.33–58.98) | 3920 (3105–4499) | 1.79 (1.42–2.06) | 32.93 (3.41–52.72) | 83.8 (67.12–96.4) | 40.61 (32.49–46.85) | 25.67 (2.27–44.11) |
| Central Latin America | 3927 (3269–4645) | 1.65 (1.38–1.96) | 44.69 (21.08–69.62) | 3038 (2529–3589) | 1.3 (1.08–1.53) | 30.08 (7.57–52.46) | 76.73 (62.57–91.25) | 31.74 (25.98–37.71) | 28.6 (6.83–50.76) |
| Central Sub-Saharan Africa | 630 (390–864) | 1.2 (0.74–1.64) | 3.84(− 23.17–36.26) | 574 (355–783) | 1.16 (0.71–1.56) | 1.05(− 24.05–29.46) | 15.98 (9.98–21.98) | 27.62 (17.1–37.65) | 0.37(− 26.39–32.62) |
| East Asia | 19,712 (14445–24,287) | 0.94 (0.69–1.16) | 32.75(− 28.14–71.32) | 14,109 (10739–17,150) | 0.68 (0.52–0.83) | 6.05(− 39.47–35.18) | 363.76 (271.11–439.32) | 17.25 (12.7–20.81) | 6.96(− 42.07–39.48) |
| Eastern Europe | 5358 (4643–6083) | 1.57 (1.35–1.78) | 42.09 (21.48–60.32) | 3986 (3373–4508) | 1.15 (0.97–1.31) | 31.27 (10.61–49.17) | 98.84 (82.51–112.1) | 29.54 (24.6–33.43) | 27.19 (10.77–44.01) |
| Eastern Sub-Saharan Africa | 2034 (1437–2501) | 1.28 (0.91–1.56) | 10.84(− 21.33–37.13) | 1889 (1348–2308) | 1.25 (0.89–1.52) | 9.12(− 21.64–35.2) | 50.82 (35.96–62.75) | 28.94 (20.6–35.64) | 6.58(− 25.49–36.05) |
| High-income Asia Pacific | 9191 (7132–10,888) | 1.96 (1.58–2.3) | 10.62(− 13.64–28.79) | 6562 (5165–7282) | 1.32 (1.07–1.45) | −3.08(− 21.57–5.56) | 113.04 (93.38–123.29) | 26.62 (22.07–28.98) | −8.67(− 27.89 - -0.88) |
| High-income North America | 30,394 (26016–36,835) | 4.8 (4.12–5.87) | 11.22(− 4.48–41.32) | 19,942 (18012–22,920) | 3.07 (2.8–3.58) | −1.27(− 6.53–21.95) | 388.96 (360.5–478.32) | 63.18 (58.79–78.56) | −7.85(− 12.97–21.41) |
| North Africa and Middle East | 6373 (4991–7641) | 1.49 (1.17–1.77) | 14.95(− 23.27–42.18) | 5012 (3938–5969) | 1.22 (0.96–1.44) | 2.91(− 29.84–26.14) | 130 (101.74–157.35) | 28.4 (22.27–34.07) | 0.13(− 33.47–23.52) |
| Oceania | 72 (48–115) | 1.01 (0.69–1.55) | − 0.74(− 18.92–23.18) | 63 (42–100) | 0.94 (0.64–1.43) | −1.9(− 19.53–21.1) | 1.83 (1.22–3.02) | 22.99 (15.54–36.69) | −2.57(− 21–22.71) |
| South Asia | 13,368 (9787–15,941) | 0.95 (0.69–1.13) | 16.5(− 18.11–42.11) | 11,734 (8615–13,925) | 0.86 (0.62–1.02) | 8.87(− 24.09–31.24) | 305.84 (228.24–362.7) | 20.67 (15.34–24.47) | 10.05(− 23.54–32.56) |
| Southeast Asia | 5003 (4174–6594) | 0.82 (0.68–1.09) | 14.96(− 11.79–37.09) | 4194 (3495–5587) | 0.71 (0.59–0.95) | 7.02(− 17.05–25.43) | 108.86 (90.98–142.69) | 16.9 (14.12–22.27) | 4.26(− 21.38–23.88) |
| Southern Latin America | 2212 (1728–2837) | 2.66 (2.08–3.41) | 28.04(− 2.34–64.15) | 1739 (1584–2003) | 2.07 (1.88–2.37) | 14.63 (1.17–31.88) | 38.12 (34.97–44.3) | 46.4 (42.61–53.99) | 12.67(− 1.76–32.19) |
| Southern Sub-Saharan Africa | 1267 (905–1467) | 2.24 (1.6–2.59) | 22.37(−3.98–45.5) | 1108 (788–1283) | 2.04 (1.45–2.35) | 20.07(− 4.68–43.35) | 29.17 (20.71–33.88) | 48.73 (34.63–56.49) | 17.56(− 9.33–38.88) |
| Tropical Latin America | 5004 (4350–5394) | 2.06 (1.78–2.22) | 46.2 (23.92–56.74) | 4018 (3400–4313) | 1.67 (1.41–1.8) | 35.83 (12.05–45.67) | 96.79 (85–105.43) | 39.11 (34.15–42.37) | 28.34 (11.91–36.39) |
| Western Europe | 38,981 (31727–44,710) | 4.24 (3.51–4.9) | 29.9 (10.88–48.41) | 25,996 (21281–27,914) | 2.64 (2.22–2.82) | 15.62(−2.93–21.83) | 461.63 (397.99–495.38) | 52.87 (46.52–56.55) | 7.97(− 5.58–15.07) |
| Western Sub-Saharan Africa | 1705 (1340–2074) | 0.91 (0.72–1.11) | 15.57(− 9.48–40.42) | 1536 (1189–1882) | 0.86 (0.67–1.05) | 12.22(− 12.14–35.43) | 41.44 (31.75–51.23) | 20.47 (15.76–25.1) | 11.51(− 13.72–37.56) |