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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Pharm Sci. 2020 Sep 12;109(12):3716–3727. doi: 10.1016/j.xphs.2020.09.011

Figure 2.

Figure 2.

(a) Stern-Volmer constants for freshly prepared and incubated EBOV-GP vaccines for lyophilized (EBOV-GP LYO), liquid in ammonium acetate (EBOV-GP LIQ), and liquid in PBS (EBOV-GP PBS) compared to unfolded control in 8M urea. (b) Comparison of the Stern-Volmer constant with monomer folding variant area from size-exclusion chromatograms shows a positive correlation between degree of unfolding and the fraction of the total soluble protein present as monomeric folding variants. Error bars are standard deviation from the average of three replicates.