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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Pharm Sci. 2020 Sep 12;109(12):3716–3727. doi: 10.1016/j.xphs.2020.09.011

Figure 4.

Figure 4.

(a) EBOV-GP near-UV circular dichroism spectra for unincubated and incubated for 12 weeks at 40°C samples in lyophilized (EBOV-GP LYO), liquid in ammonium acetate with trehalose (EBOV-GP LIQ), and liquid in PBS (EBOV-GP PBS) formulations. (b) Changes in near-UV CD were assessed by monitoring the wavelength corresponding to the first intercept in the second derivative of each spectrum (referring to an inflection point in the CD spectrum) over the incubation period. Error bars represent the standard deviation from n = 8 replicates.