Figure 7.

Representative size-exclusion chromatograms of unincubated liquid in PBS formulations for (a) MARV-GP and (b) SUDV-GP. Peak classifications were made using SEC-MALS molecular weight data (gray markers, right axis). No distribution of oligomerization states was seen in MARV-GP samples, so only total peak area was used for area analyses. For SUDV-GP, high molecular weight (HMW) species were defined as any peak eluted between 8 and 12.2 minutes, monomer was defined as the peak between 12.2 and 14.2 minutes, and monomer folding variants were those peaks eluted between 14.2 and 18 minutes, shown in boxes in (b).