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. Author manuscript; available in PMC: 2021 Aug 21.
Published in final edited form as: ACS Chem Biol. 2020 Jul 28;15(8):2299–2310. doi: 10.1021/acschembio.0c00537

Figure 6.

Figure 6.

Comparison of the universal and the conventional 2G12-based CAR-NK cells in killing subtype B gp160-expressing cells. Cells were co-cultured eight hours at 1:1, 5:1, or 25:1 E:T ratios. The cytotoxicity was determined based on the percentage of gp160-positive cells killed by CAR-NK cells. Data are presented as the mean ± SD of triplicate samples. Statistical significance is calculated by two-way ANOVA and Tukey’s post-hoc analysis. **** p<0.0001 vs. non-transduced NK cells. ## p<0.01 comparing the percentages of cytotoxicity of 2G12-CAR-NK cells to that of DNP-CAR-NK cells at the 25:1 E:T ratio.