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. 2021 May 26;21:611. doi: 10.1186/s12885-021-08368-5

Table 4.

Analysis by medical history. Mutations are reported according to personal and familial history for cancer

Mutations
C4/C5 VUS no
Personal history
Yes 1 5 4
No/unknown 7 10 33
Familial history
Yes 4 5 14
No/unknown 4 10 23

C4/C5 Likely pathogenic (C4) or pathogenic (C5) according to the IARC classification, VUS Variants of uncertain significance