Fig. 2.

Alternative path activation related to ErbB signaling pathway: STAT5A. a: Boxplots of the path values of paths ErbB signaling pathway: STAT5A and ErbB signaling pathway: STAT5A* for the tumor and normal tissue samples across the three cancers. b: Graphical representation of paths ErbB signaling pathway: STAT5A (in the dark orange box) and ErbB signaling pathway: STAT5A* (in the light orange box) including gene differential expression across the three cancers. Red, blue and white nodes correspond to significant up- or down-regulated genes, or non-significant nodes, respectively. Red and blue arrows represent paths significantly up- or down-activated. c: Boxplots of the activity values of functions Lactation and Transcription, which are promoted by paths ErbB signaling pathway: STAT5A and ErbB signaling pathway: STAT5A*, for the tumor and normal tissue samples across the three cancers