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. Author manuscript; available in PMC: 2021 May 26.
Published in final edited form as: World Neurosurg. 2019 Nov 27;135:e174–e180. doi: 10.1016/j.wneu.2019.11.089

Table 2.

Multivariate Analysis of Factors Associated with Prognosis and Control

Metric HR P value
FFP (per patient)
 Melanoma 4.35 0.003
 Salvage post-WBRT – ns
FFNMs
 Number of BMs, prior WBRT, histology, volume – ns
Overall survival
 Salvage post-WBRT 1.61 0.019
 KPS score 0.98 0.017
 Total volume 1.03 0.031
 Number of BMs, age, histology – ns
FFARE
 Melanoma 2.13 0.002
 Salvage post-WBRT 1.63 0.005
 Number of BMs, volume, age – ns

HR, hazard ratio; FFP, freedom from progression; WBRT, whole brain radiotherapy; ns, not significant; FFNM, freedom from new metastasis; BM, brain metastasis; KPS, Karnofsky Performance Status Scale; FFARE, freedom from adverse radiation effect.