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. 2021 May 26;19:119. doi: 10.1186/s12916-021-01989-4

Table 1.

Characteristics of women with and without premenstrual disorders (PMD)

Population cohort Sibling cohort a
Reference N (%) PMD N (%) Reference N (%) PMD N (%)
Total number 1,472,310 18,628 631,236 7,674
Year of birth
 1960–1964 239,959 (16.3) 4346 (23.3) 80,813 (12.8) 1471 (19.2)
 1965–1970 255,554 (17.4) 5080 (27.3) 111,933 (17.7) 2142 (27.9)
 1970–1974 243,458 (16.5) 4097 (22.0) 112,549 (17.8) 1837 (23.9)
 1975–1979 218,052 (14.8) 2428 (13.0) 103,626 (16.4) 1097 (14.3)
 1980–1984 216,518 (14.7) 1628 (8.7) 106,187 (16.8) 753 (9.8)
 1985–1990 298,769 (20.3) 1049 (5.6) 116,128 (18.4) 374 (4.9)
Educational level
 Primary 226,819 (15.4) 2304 (12.4) 104,799 (16.6) 957 (12.5)
 High school 604,802 (41.1) 9435 (50.6) 262,378 (41.6) 3910 (51.0)
 College and beyond 379,324 (25.8) 6005 (32.2) 166,447 (26.4) 2508 (32.7)
 Unknown 261,365 (17.8) 884 (4.7) 97,612 (15.5) 299 (3.9)
Region of residency
 South 342,159 (23.2) 3602 (19.3) 150,946 (23.9) 1514 (19.7)
 Middle 825,202 (56.0) 11,293 (60.6) 347,545 (55.1) 4597 (59.9)
 North 304,949 (20.7) 3733 (20.0) 132,745 (21.0) 1563 (20.4)
History of injury
 No 1,327,241 (90.1) 14,169 (76.1) 571,236 (90.5) 5870 (76.5)
 Yes 145,069 (9.9) 4459 (23.9) 60,000 (9.5) 1804 (23.5)
PYs (%) PYs (%) PYs (%) PYs (%)
Psychiatric comorbiditiesb
 No 13,820,488 (95.6) 83,418 (89.3) 6,050,657 (95.9) 34,195 (89.7)
 Yes 636,709 (4.4) 10,005 (10.7) 261,787 (4.1) 3932 (10.3)

N number, PYs person-years

aSibling cohort was restricted to women with at least one identifiable full sister in the population cohort

bPsychiatric disorder was considered as time-varying, i.e., person-years from the cohort entry if any diagnosis of psychiatric disorders occurred before cohort entry, or person-years from the date of diagnosis if any diagnosis of psychiatric disorders occurred during the follow-up