Table 4.
Toxicity and adverse reactions between the gemcitabine and docetaxel groups, n (%)
Toxicity (grade) | Gemcitabine + platinum (n=56), n (%) | Docetaxel + platinum (n=57), n (%) | P |
---|---|---|---|
Leucopenia | |||
0 | 0 | 0 | 0.483 |
1-2 | 40 (71.4) | 44 (77.2) | |
3-4 | 16 (28.6) | 13 (22.8) | |
Anemia | |||
0 | 3 (5.4) | 2 (3.5) | 0.633 |
1-2 | 53 (94.6) | 55 (96.5) | |
3-4 | 0 | 0 | |
Thrombocytopenia | |||
0 | 0 | 2 (3.5) | 0.159 |
1-2 | 49 (87.5) | 52 (91.1) | |
3-4 | 7 (12.5) | 3 (5.4) | |
Vomiting | |||
0 | 0 | 0 | 0.775 |
1-2 | 51 (91.1) | 51 (89.5) | |
3-4 | 5 (8.9) | 6 (10.5) | |
Renal damage | |||
0 | 52 (92.9) | 54 (94.7) | 0.679 |
1 | 4 (7.1) | 3 (5.3) | |
2-4 | 0 | 0 | |
Liver function damage | |||
0 | 48 (85.7) | 50 (87.7) | 0.753 |
1 | 8 (14.3) | 7 (12.3) | |
2-4 | 0 | 0 | |
Sensory neuritis | |||
0 | 55 (98.2) | 50 (87.7) | 0.03 |
1 | 1 (1.8) | 7 (12.3) | |
2-4 | 0 | 0 |