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HFD feeding induced a metabolic state associated with alterations in reproductive organs. Metabolic evaluation of HFD-fed compared with chow-diet (control) mice: (a) body weight and (b) glucose tolerance test. (c) Representative images of accumulation of fatty tissue in the abdominal cavity of HFD-fed mice. All graphs represent the mean ± s.d., n = 4. Data were statistically analyzed with an unpaired t-test: *P < 0.05, **P < 0.01. s.d.: standard deviation; HFD: high-fat diet.
