. Author manuscript; available in PMC: 2021 May 26.

Published in final edited form as: Lancet Haematol. 2020 May;7(5):e408–e417. doi: 10.1016/S2352-3026(20)30064-8

Table 1:

Critical appraisal of articles reviewed by use of the Joanna Briggs Institute recommendations

	CIPN measure tested	Eligibility defined	Sample and setting described	Comparison groups defined	Objective criteria for measuring condition	Adequate training of study staff	Attention to procedural fidelity	Strategies to consider confounders	Appropriate statistics and statistical power	Total score
Gilchrist et al (2009)⁴²	ped-mTNS	1·0	1·0	0·0	1·0	NA^*	0·0	0·5	0·0^†	3·5
Gilchrist and Tanner (2013)³⁵	ped-mTNS	1·0	1·0	1·0	1·0	1·0	1·0	0·5	0·0	6·5
Gilchrist et al (2014)³⁴	ped-mTNS and CTCAE version 3.0	1·0	1·0	0·0	1·0	1·0	0·0	0·5	0·0	4·5
Gilchrist and Tanner (2018)⁴³	ped-mTNS	1·0	1·0	0·0	1·0	0·0	0·0	0·5	0·0	3·5
Lieber et al (2018)⁴⁴	rPed-mTNS, nerve conduction studies, quantitative sensory testing	1·0	1·0	1·0	0·0	0·0	0·0	0·5	0·0	3·5
Smith et al (2013)³³	TNS-PV, CTCAE version 4.0, the Balis scale, and the FACES scale	1·0	1·0	0·0	1·0	1·0	1·0	0·5	1·0	6·5
Wright et al (2017)⁴⁵	Gait analysis	1·0	1·0	1·0	1·0	0·0	0·0	0·5	0·0	4·5

A score of 0 means that the characteristic is not shown by the study. A score of 1 means that the characteristic is shown by the study. A score of 0·5 means that the characteristic is partially shown by the study. CIPN=chemotherapy-induced peripheral neurotoxicity. ped-mTNS=pediatric-modified Total Neuropathy Score. NA=not applicable. CTCAE=National Cancer Institute Common Terminology Criteria for Adverse Events. rPed-mTNS=reduced pediatric-modified Total Neuropathy Score. TNS-PV=Total Neuropathy Score-pediatric vincristine.

Scores obtained by a single reviewer and validated by a second reviewer. Training of study staff was not required.

^†

This study by Gilchrist and colleagues was a pilot study.