Table 2.
Risk factor characteristics by Chronic Kidney Disease (CKD) status and by heart failure status in the Multi-Ethnic Study of Atherosclerosis
| Variables | CKD Group (n=325) | Non-CKD Group (n=5,179) | ||||
|---|---|---|---|---|---|---|
| HF (n=39) | No HF (n=286) | P value | HF (n=180) | No HF (n=4,999) | P value | |
| Age (years) | 73.3±7.0 | 72.9±8.1 | 0.8 | 67.9±8.7 | 61.4±10.0 | <0.001 |
| Sex (Male) | 64.1% | 40.2% | 0.005 | 60.0% | 48.5% | 0.002 |
| BMI (kg/m2) | 29.6±5.6 | 28.4±5.4 | 0.2 | 29.5±5.6 | 28.2±5.4 | <0.001 |
| Smoking | 5.1% | 8.7% | 0.6 | 13.9% | 12.8% | 0.7 |
| SBP (mmHg) | 144±26.8 | 139±24.7 | 0.16 | 137±21.9 | 125±20.8 | <0.001 |
| Heart rate (bpm) | 62.7±10.7 | 63.8±11.3 | 0.6 | 65.9±10.5 | 63.0±9.5 | <0.001 |
| Diabetes | 35.9% | 19.6% | 0.02 | 31.7% | 12% | <0.001 |
| +NT-proBNP (pg/mL) | 331 (215, 510) | 143 (127, 161) | <0.001 | 126 (106, 149) | 45.6 (44.2, 47.0) | <0.001 |
| eGFR (mL/min/1.73m2) | 46.6±12.2 | 49.2±10.8 | 0.2 | 86.2±15.0 | 92.6±15.5 | <0.001 |
Data presented as mean ± SD or frequency (%) unless otherwise noted. Abbreviations: CKD = chronic kidney disease; HF = heart failure; BMI = body mass index; SBP = systolic blood pressure; eGFR = estimated glomerular filtration rate based on serum creatinine and cystatin C levels [28]; NT-proBNP = N-terminal pro-brain natriuretic peptide; CKD defined as eGFR < 60 ml/min/1.73m2;
+
P values calculated by comparing mean values of log transformed NT-proBNP levels and values shown as geometric means (95% CI).