Sequences of stapled peptides and a linear peptide with their specific functionsa.
Peptide code | Sequence | Functions |
---|---|---|
SP1 |
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Inhibitor |
SP2 |
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Inhibitor |
SP3 |
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Inhibitor |
SP4 |
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Inhibitor |
SP5 |
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Inhibitor |
SP6 |
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Inhibitor |
LP1 | Ac-L(Ant)FFK-CONH2 | Control |
Standard amino acids are represented by their one-letter code, Ant = anthranilic acid, N-Me = N-methylation, Ac = acetyl group. Dicarboxylic acids, COOH–(CH2)n–COOH, used are adipic acid (n = 4), glutaric acid (n = 3) and succinic acid (n = 2).