Table 2.
Intrinsic properties of striatal CINs in the Er81 cKO and the control mice at P6
| P6 | Ctl | n | Er81 cKO | nrepresent Wilcoxon rank sum test, and | Statistica | p |
|---|---|---|---|---|---|---|
| Resting membrane potential (mV) | −49.18 ± 1.03 | 13 | −47.10 ± 1.49 | 9 | t(20) = 1.19 | 0.248 |
| Membrane capacitance (pF) | 63.06 ± 3.76 | 16 | 63.22 ± 4.41 | 17 | t(31) = 0.03 | 0.979 |
| Membrane resistance (mΩ) | 209.72 ± 13.37 | 16 | 217.19 ± 15.24 | 17 | t(31) = 0.37 | 0.716 |
| AP threshold (mV) | −37.95 ± 1.03 | 13 | −34.82 ± 1.36 | 9 | z = 1.90 | 0.062 |
| AP amplitude (mV) | 60.24 ± 2.53 | 13 | 62.94 ± 3.15 | 9 | t(20) = 0.67 | 0.508 |
| AP rise to peak (ms) | 1.15 ± 0.07 | 13 | 1.14 ± 0.11 | 9 | t(20) = 0.09 | 0.929 |
| AP fall to threshold (ms) | 3.07 ± 0.13 | 13 | 3.14 ± 0.24 | 9 | z = 0.20 | 0.841 |
| AHP rise time constant (ms) | 3.79 ± 0.45 | 13 | 3.28 ± 0.44 | 9 | t(20) = 0.77 | 0.449 |
| AHP decay time constant (ms) | 737.2 ± 184.6 | 13 | 381.0 ± 75.1 | 9 | z = 0.67 | 0.504 |
| Spontaneous AP rate (Hz, whole-cell) | 1.29 ± 0.19 | 13 | 3.34 ± 0.50 | 9 | t(20) = 4.32 | 3.3 × 10−4 |
| Spontaneous AP rate (Hz, cell-attached) | 1.04 ± 0.28 | 8 | 1.07 ± 0.23 | 16 | z = 0.09 | 0.927 |
| First AP latency (ms) | 3.79 ± 0.21 | 13 | 3.93 ± 0.49 | 9 | z = 0.67 | 0.503 |
| AP recovery time (s) | 7.91 ± 2.77 | 12 | 4.01 ± 1.03 | 9 | z = 1.31 | 0.189 |
| Preceding depolarization (mV) | 29.27 ± 2.63 | 13 | 25.92 ± 3.18 | 9 | t(20) = 0.81 | 0.425 |
az statistics represent Wilcoxon rank sum test, and t statistics represent two-sample t test.