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. 2021 May 19;41(20):4487–4499. doi: 10.1523/JNEUROSCI.2853-20.2021

Table 1.

Clinical and demographic information

Characteristics AN (n = 22)
BN (n = 33)
HC (n = 30)
Analysis
Mean SD Mean SD Mean SD Χ2(df), F(df), W, t(df) p Value
Age (years) 24.6 4.7 23.6 3.9 23.9 3.5 Χ2(2) = 0.8 0.69
BMI (kg/m2) 16.4 1.4 22.0 2.4 21.9 2.1 Χ2(2) = 48.4 <0.001
IQa 116 5 114 5 114 5 Χ2(2) = 3.2 0.21
Age of onset (years) 15.6 2.4 16.2 3.1 t(51.8) = −0.8 0.42
Illness duration (years) 9.0 5.8 7.4 4.0 t(34.4) = 1.1 0.27
Beck Depression Inventory 35.3 12.0 32.7 10.5 2.4 2.8 Χ2(2) = 57.7 <0.001
Trait Anxiety Inventory 63.1 10.4 62.8 7.3 33.0 6.9 F(2) = 151.1 <0.001
Barratt Impulsiveness Scale 66.2 14.0 68.4 11.1 56.7 6.3 F(2) = 10.4 <0.001
Eating Disorder Examination Questionnaire 4.4 0.8 4.6 0.8 0.2 0.2 Χ2(2) = 58.0 <0.001
Eating disorder examination ratingsb
Objective binge-eating episodes 38.1 47.9 23.0 29.1 W = 317.5 0.43
Subjective binge-eating episodes 9.5 12.8 6.6 6.2 W = 341.5 0.93
Vomiting episodes 43.5 51.6 24.2 31.0 W = 304.0 0.31
Laxative episodes 1.1 3.4 2.0 3.9 W = 421.5 0.18
Exercise episodes 7.4 13.6 10.9 9.4 W = 478.5 0.04
N % N % N % Χ2(df) p Value
Comorbid diagnoses
Anxiety disorder 3 13.6 3 9.1 Χ2(1) = 0.3 0.69
Major depressive episode 15 68.2 16 48.5 Χ2(1) = 2.1 0.15
Personality disorder 2 9.1 5 15.2 Χ2(1) = 0.4 0.69
Any current treatment 13 59.0 15 45.5 Χ2(1) = 1.0 0.32
Psychotherapy 9 40.9 9 27.3 Χ2(1) = 1.1 0.29
Medication 10 45.5 10 30.3 Χ2(1) = 1.3 0.25
Prior restrictive AN 14 63.6 10 30.3 Χ2(1) = 6.0 0.01

Group differences were evaluated using one-way ANOVA and, for non-normally distributed data, the nonparametric Kruskal–Wallis test. The two-samples t test (two-sided), Mann–Whitney U test, and χ2 test were used to assess differences between AN and BN groups. For type and dose of prescribed medications, see Extended data Table 1-1.

aEstimated full-scale IQ from the National Adult Reading Test.

bED examination ratings reflect counts over the previous 28 d.