Table 1.
Baseline characteristics. In-hospital anticoagulation.
| Myocardial Injury | p-Value | ||
|---|---|---|---|
| With (n = 72) |
Without (n = 259) |
||
| Characteristic | |||
| Age (years), mean ± SD | 75 ± 11 | 61 ± 17 | 0.001 |
| Male sex, n (%) | 50 (69.4) | 145 (56.0) | 0.043 |
| BMI, median (IQR) | 28.6 (25.8–30.4) | 27.0 (24.2–29.8) | 0.071 |
| Current smoker, n (%) | 2 (2.8) | 7 (2.7) | 1.000 |
| Diabetes, n (%) | 28 (38.9) | 39 (15.1) | 0.001 |
| Hypertension, n (%) | 54 (75.0) | 107 (41.3) | 0.001 |
| Hypercholesterolemia, n (%) | 33 (45.8) | 70 (27.0) | 0.004 |
| Chronic kidney disease, n (%) | 34 (47.2) | 35 (13.5) | 0.001 |
| Hemodialysis, n (%) | 4 (5.6) | 2 (0.8) | 0.022 |
| Atrial fibrillation, n (%) | 7 (9.7) | 13 (5.0) | 0.161 |
| Previous stroke or TIA, n (%) | 10 (13.9) | 6 (2.3) | 0.001 |
| Previous AMI, n (%) | 11 (15.3) | 8 (3.1) | 0.001 |
| Previous PCI, n (%) | 14 (19.4) | 10 (3.9) | 0.001 |
| Previous CABG, n (%) | 4 (5.6) | 2 (0.8) | 0.022 |
| Previous PVD, n (%) | 5 (16.7) | 2 (2.2) | 0.001 |
| Previous COPD or Asthma, n (%) | 11 (15.3) | 32 (12.4) | 0.553 |
| Previous pneumonia, n (%) | 3 (4.2) | 3 (3.5) | 0.732 |
| Previous heart failure, n (%) | 12 (16.7) | 10 (3.9) | 0.001 |
| Previous bleeding | 9 (12.5) | 9 (3.5) | 0.006 |
| LVEF, mean ± SD | 53 ± 9 | 57 ± 8 | 0.106 |
| Previous PE, n (%) | 2 (2.8) | 3 (1.2) | 0.299 |
| Active cancer, n (%) | 10 (13.9) | 12 (4.6) | 0.013 |
| Organ transplant, n (%) | 3 (4.2) | 9 (3.5) | 0.728 |
| Charlson Comorbidity Index, median (IQR) | 5 (4–7) | 2 (1–4) | 0.001 |
| Anticoagulation | |||
| Any anticoagulants, n (%) | 57 (79.2) | 229 (88.4) | 0.051 |
| LMWH | 58 (81.0) | 225 (87.0) | 0.178 |
| DOAC | 0 | 4 (1.5) | 0.580 |
| Prophylactic indication | 46 (80.7) | 203 (88.6) | 0.001 |
AMI, acute myocardial infarction; BMI, body mass index; CABG, coronary artery bypass graft; COPD, chronic obstructive pulmonary disease; DOAC, direct-acting oral anticoagulants; IQR, interquartile range; LMWH, low-molecular-weight heparin; LVEF, left ventricular ejection fraction; PCI, percutaneous coronary intervention; PE, pulmonary embolism; PVD, peripheral vascular disease I; SD, standard deviation; TIA, transient ischemic accident.