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. 2021 May 13;13(5):1637. doi: 10.3390/nu13051637

Figure 7.

Figure 7

Dietary FA restriction enhances growth of orthotopically transplanted M-Wnt mammary tumors and minimally effects tumor metabolomic profile. Body weight of mice fed different folate diets for 3 weeks (A) (n = 10–14/group). Body composition determined by echo MRI (B) (n = 10–14/group). Ex vivo tumor volume (C) and weight (D) (n = 9–13/group). Summary of tumor metabolomics (E), PCA of tumor metabolomics (F) (n = 6/group). Tumor metabolite levels of 5-mTHF (G) (n = 6–7/group), different letters indicate significant differences.