Effects of reaction parametersa.
| ||
|---|---|---|
| Entry | Variation from the standard conditions | 3aa yieldb |
| 1 | None | 83% (82%)c |
| 2 | HFIP instead of HFIP/CH2Cl2 (6 : 4) | 76% |
| 3 | CF3CH2OH instead of HFIP | 65% |
| 4 | (CH3)2CHOH instead of HFIP | 9% |
| 5 | n-Bu4NPF6 instead of n-Bu4NBF4 | 58% |
| 6 | Platinum plate cathode instead of graphite rod cathode | 88%c |
| 7 | Under air | 80%c |
| 8 | No electric current | NR |
Reaction conditions: graphite rod anode, graphite rod cathode, constant current = 10 mA. 2a (0.3–0.4 mmol), 1a (1.5 equiv.), n-Bu4NBF4 (1.0 equiv.), solvent (10 mL), rt, 2 h, under N2.
NMR yields using 1,1,2,2-tetrachloroethane as the internal standard.
Isolated yield.