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. 2020 Mar 23;11(15):3909–3913. doi: 10.1039/d0sc01078b

Effects of reaction parametersa.

graphic file with name d0sc01078b-u1.jpg
Entry Variation from the standard conditions 3aa yieldb
1 None 83% (82%)c
2 HFIP instead of HFIP/CH2Cl2 (6 : 4) 76%
3 CF3CH2OH instead of HFIP 65%
4 (CH3)2CHOH instead of HFIP 9%
5 n-Bu4NPF6 instead of n-Bu4NBF4 58%
6 Platinum plate cathode instead of graphite rod cathode 88%c
7 Under air 80%c
8 No electric current NR
a

Reaction conditions: graphite rod anode, graphite rod cathode, constant current = 10 mA. 2a (0.3–0.4 mmol), 1a (1.5 equiv.), n-Bu4NBF4 (1.0 equiv.), solvent (10 mL), rt, 2 h, under N2.

b

NMR yields using 1,1,2,2-tetrachloroethane as the internal standard.

c

Isolated yield.