Table 2a.
Correlation analyses: Partial correlation between normally distributed GABA+/Cr levels within dorsomedial/dorsoanterolateral prefrontal cortex and verbal memory scores in CN (N = 14) and high-AD risk group (N = 24)
| Scales | Subscales | Pearson’s r (significance level) | |
|---|---|---|---|
| Covariates: Age and brain tissue volumes (WM, GM, and CSF) | CN | High-AD risk | |
| California Verbal Learning Test–II (CVLT-II) | Immediate recall | 0.26 (0.5) | 0.60 (0.02*) |
| Long delayed free recall | −0.24 (0.5) | 0.70 (0.005**) | |
| Short delayed free recall | −0.25 (0.5) | 0.64 (0.01**) | |
| Covariates: Age, depression and brain tissue volumes (WM, GM, and CSF) | CN | High-AD risk | |
| California Verbal Learning Test–II (CVLT-II) | Immediate recall | 0.40 (0.3) | 0.57 (0.04*) |
| Long delayed free recall | −0.18 (0.7) | 0.69 (0.009**) | |
| Short delayed free recall | −0.21 (0.6) | 0.62 (0.02*) | |
The correlation analyses are repeated with depression scores as a covariate in addition to age and whole brain tissue volumes. The Bonferroni-adjusted significance level P value <0.017 is applied here. Bonferroni-adjusted significance levels (P value < 0.017) are represented with double asterisks** and bold format. Significance levels (P value < 0.05) are represented with single asterisk*.