Table 3.

Alternative diagnoses among 105 patients referred with suspected HE/SREAT

Alternative clinical diagnoses	N (%)
Neurodegenerative disorder	18 (17.1%)
Alzheimer disease (5)
Fronto-temporal dementia (1)
Primary progressive aphasia (2)
Lewy body dementia (2)
Posterior cortical atrophy (1)
Vascular dementia (1)
Probable Creutzfeldt–Jakob disease (1)
Other neurodegenerative disorder (5)
Functional neurological disorder	20 (19%)
Subjective cognitive complaints	14 (13.3%)
Fibromyalgia/chronic fatigue/chronic pain syndromes	12 (11.4%)
Psychiatric disorder	11 (10.5%)
Depression (3)
Generalized anxiety disorder (2)
Bipolar disorder (2)
Obsessive compulsive disorder (1)
Schizoaffective disorder (1)
Schizophreniform disorder (2)
Sleep disorder, in combination with other diagnosis	10 (9.5%)
Obstructive sleep apnoea + functional (3)
Obstructive sleep apnoea + fibromyalgia + depression (2)
Obstructive sleep apnoea + anxiety (1)
Obstructive sleep apnoea + narcolepsy (1)
Primary hipersomnia + functional tremor + fibromyalgia (1)
Insomnia + functional tremor + depression (1)
Insomnia +subjective cognitive (1)
Other medical condition	10 (9.5%)
Severe hypothyroidism (2)
Radiation leucoencephalopathy (1)
Post-surgical movement disorder (1)
Side effects antiepileptic drugs (1)
Mast cell activation disorder (1)
Static encephalopathy after intracranial haemorrhage + status epilepticus (1)
Intracranial hypotension (1)
Leucoencephalopathy (toxic/vascular) (1)
Central pontine myelinolysis + functional tremor and spells (1)
Genetic/developmental disorder with behavioural/cognitive symptoms	8 (7.6%)
Trisomy 21 (1)
Trisomy 2 (1)
Mitochondrial cytopathy (1)
Adult onset neuronal intra-nuclear inclusion disease (1)
Autism spectrum disorder (1)
Other developmental disorder (3)
Epilepsy	2 (1.9%)
Idiopathic focal epilepsy (1)
Focal epilepsy secondary to meningioma (1)