Table 7.
CSF findings in patients with alternative diagnosis without clinical improvement after immunotherapy (non-responders) and patients with autoimmune CNS disorders who experienced improvement (responders)
| Diagnostic test | Non-responders (n = 12) | Responders (n = 16) | Total (n = 28) | P value |
|---|---|---|---|---|
| CSF inflammatorya | 0 | 6 (37.5) | 6 (37.5) | 0.02 |
| WBCs, >5 cells/μl | 0 | 4 (25) | 4 (25) | 0.11 |
| Protein level, >50 mg/dl | 5 (41.7) | 9 (56.3) | 14 (50) | 0.7 |
| Positive OCB | 0/11 | 1/14 (7.1) | 1/25 (4) | >0.99 |
| Elevated IgG synthesis rate | 0/11 | 1/14 (7.1) | 1/25 (4) | >0.99 |
Categorical data is provided as number (percentage).
WBC, white blood cells; OCB, oligoclonal bands.
a
CSF inflammatory: WBC, >5 cells/μl, positive OCBs, high IgG index or synthesis rate.