Table 1.
Five SNPs with statistically significant association with skin pigmentation on the upper arm, lower arm, or forehead in 299 Pakistani individuals from three subpopulations (Baloch, Pashtun, and Punjabi).
Upper Arm | Lower Arm | Forehead | |||||
---|---|---|---|---|---|---|---|
Gene | SNP | Adjusted R2 | Sign.1 | Adjusted R2 | Sign. 1 | Adjusted R2 | Sign. 1 |
TYR | rs1042602 | 0.13 | *** | 0.11 | ** | 0.071 | ** |
GRM5 | rs10831496 | 0.029 | – | 0.047 | * | 0.014 | – |
HERC2 | rs12913832 | 0.025 | – | 0.016 | – | 0.064 | * |
SLC24A5 | rs1426654 | 0.16 | *** | 0.10 | ** | 0.082 | ** |
SLC45A2 | rs16891982 | 0.075 | ** | 0.028 | – | 0.058 | ** |
1 Statistical significance (Sign.) after Bonferroni correction: * p < 0.05, ** p < 10−3, *** p < 10−6.