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LC-MS profiles of Fab fragments originating from IgA clones present in human milk. (A) Profile of IgA clones detected in the unpasteurized milk of Patient 1; (B) SARS-CoV-2 antigen-specific affinity purification yields specific clones (orange line; right y-axis), distinct from the depleted flow-through fraction (green line, left y-axis); (C) Overlay of the three profiles reveals the high specificity of a few antigen-specific clones.
