Aza-Henry reaction optimization.

Entrya	PC	x (mol%)	Solvent	λ (nm)	Convb. (%)
1	ICG	10	CH3NO2c	810	16
2	IR-813	10	CH3NO2c	810	28
3	DTCCI	10	CH3NO2c	810	14
4	cy746	10	CH3NO2c	810	57
5	cy746	10	CH3NO2c	780	14
6	cy746	10	CH3NO2c	940	<5
7	cy746	10	DCM	810	48
8	cy746	10	DMF	810	n.r
9	cy746	10	MeOH	810	28
10	cy746	10	DMSO	810	91
11	cy746	5	DMSO	810	85
12	cy746	1	DMSO	810	67
13	cy746	—	DMSO	810	16
14d	cy746	5	DMSO	810	n.r
15e	cy746	5	DMSO	810	5

^aRun on 0.1 mmol scale.

^bConversions are determined on the crude by ¹H-NMR.

^cCH₃NO₂ is used as solvent.

^dRun in the dark.

^eRun under nitrogen atmosphere in the absence of air.