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Stability measurement by HPLC injection and gamma counter after dilution and filtration.
| Addition of 200 µL Ascorbate and Injection Solution (n = 3) 180 µg PSMA-I&T | |||
|---|---|---|---|
| T = 0 h (%) | T = 3 h (%) | T = 24 h (%) | |
| Ac-225, [225Ac]Ac-DTPA | 7.5 ± 1.0 | 7.3 ± 1.5 | 9.6 ± 2.9 |
| Radiolyzed [225Ac]Ac-PSMA-I&T | 1.8 ± 0.9 | 1.9 ± 1.0 | 1.5 ± 0.3 |
| [225Ac]Ac-PSMA-I&T | 90.2 ± 0.2 | 90.3 ± 0.3 | 89.1 ± 3.5 |
