Table 4.
Characteristics of the women according to ovarian morphology assessed at the end of the follow-up.
| Characteristic | Normalized Ovarian Morphology (n = 15) | Persistent PCOM (n = 15) | p-Value |
|---|---|---|---|
| Age at follow-up (years) | 38.1 (35–42.2) | 33.6 (28–34.9) | 0.004 |
| Age of first menorrhea (years) | 13 (12–15) | 12 (12–13) | 0.07 |
| FSH at follow-up (mIU/mL) | 6.64 (5.26–8.2) | 4.92 (4.54–5.88) | 0.04 |
| FSH at baseline (mIU/mL) | 6.90 (5.6–8.27) | 5 (3.64–5.9) | 0.006 |
| LH/FSH at follow-up | 0.70 (0.49–1.07) | 0.84 (0.75–1.8) | 0.07 |
| LH/FSH at baseline | 1.14 (0.83–1.46) | 1.66 (1.1–2.46) | 0.04 |
| TT at follow-up (ng/mL) | 0.39 (0.29–0.53) | 0.58 (0.44–0.89) | 0.01 |
| ∆TT (ng/mL) | −0.34 (−0.72–(−0.06)) | −0.01 (−0.18–0.22) | 0.003 |
| FAI at follow-up | 2.25 (1.20–2.80) | 6.83 (2.16–10.01) | 0.04 |
| ∆FAI | −2.06 (−6.68–(−0.80)) | −0.5 (−1.57–2.3) | 0.05 |
| A4 at follow-up (ng/mL) | 3.75 (2.65–4.57) | 4.92 (3.84–5.68) | 0.02 |
| OHP-17 at follow-up (ng/mL) | 1.03 (0.89–1.38) | 1.4 (1.16–1.72) | 0.04 |
| E2 at follow-up (pg/mL) | 50.75 (35.5–84.44) | 73.82 (63.21–91.28) | 0.06 |
| ∆E2 (pg/mL) | 9.27 (–0.20–38.32) | 34.82 (−4.08–48.57) | NS |
| AMH at follow-up (ng/mL) | 2.20 (1.03–2.94) | 8.57 (5.46–14.1) | 0.00002 |
| ∆AMH (ng/mL) | −5.26 (−7.04–(−2.31)) | −2.03 (−4.88–0.79) | 0.06 |
| Ovarian follicle number at follow-up (n = 30) | 11 (9–14) | 23.5 (19–28) | 0.00001 |
| Ovarian volume at follow-up (mL) | 7.49 (5.87–9.6) | 13.7 (12.39–21.09) | 0.0004 |
| Oligomenorrhea at follow-up n (%) | 3 (20%) | 9 (60%) | 0.03 |
| ↑TT/FAI at follow-up n (%) | 3 (20%) | 10 (66.67%) | 0.01 |
| E-selectin at follow-up (ng/mL) | 10.60 (6.18–12.3) | 16.65 (12.18–18.69) | 0.002 |
| E-selectin at baseline (ng/mL) | 25.76 (15.27–37.15) | 35.02 (26.59–46.20) | 0.06 |
Data are expressed as median (25–75% quartiles) or numbers (%). p < 0.05 was considered statistically significant. Abbreviations: A4, androstenedione; AMH, anti-Müllerian hormone; FAI, free androgen index; FSH, follicle-stimulating hormone; LH, luteinizing hormone; NS, statistically nonsignificant; PCOM, polycystic ovarian morphology in ultrasonography; TT, total testosterone; 17-OHP, 17-hydroxyprogesterone.