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Schematic representation of KSHV-encoded proteins that involve in host energy metabolism reprogramming during latency and lytic replication. The lytic genes (K1, K5, orf50, K8, and orf74 which encodes K1, K5, RTA, K-bZIP, and vGPCR, respectively) are shown on the top panel, and the latent genes (K12, v-miRNA, orf71, orf72, and orf73 which encodes Kaposin, v-miRNA cluster, vFLIP, vCyclin, and LANA, respectively) are shown at the bottom panel. TR, terminal repeat; kb, kilo base pair.
