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. 2021 Apr 13;12(20):6929–6948. doi: 10.1039/d1sc01203g

The distribution of 12 SNP types among 5003 unique mutations and 467 604 non-unique mutations on the S gene of SARS-CoV-2 worldwide. NU is the number of unique mutations and NNU is the number of non-unique mutations. RU and RNU represent the ratios of 12 SNP types among unique and non-unique mutations.

SNP type Mutation type N U N NU R U R NU
A > T Transversion 454 5236 9.07% 1.12%
A > C Transversion 341 2571 6.82% 0.55%
A > G Transition 700 199 015 13.99% 42.56%
T > A Transversion 356 1614 7.12% 0.35%
T > C Transition 779 19 313 15.57% 4.13%
T > G Transversion 277 1940 5.54% 0.41%
C > T Transition 542 158 898 10.83% 33.98%
C > A Transversion 313 10 301 6.26% 2.20%
C > G Transversion 156 968 3.12% 0.21%
G > T Transversion 435 34 421 8.69% 7.36%
G > C Transversion 225 6090 4.50% 1.30%
G > A Transition 425 27 237 8.49% 5.82%