Figure 4.

Spatially mixed heterogeneous dynamics within local GoC networks

(A) Example activity traces from 5 GoCs (ΔF/F, black traces) during whisking (WMI, red) and locomotion (Loco, blue), with different activity during active states as residual ΔF/F (orange) after projecting out PM1. Mean total correlation = 0.72, residual correlation = 0.07.

(B) Comparison of pairwise correlations for total (gray) and residual (orange) ΔF/F, and for shuffle control (light blue) across sessions (n = 21, N = 9 animals). Black symbols and horizontal bars show population means. Difference in total and residual correlation for all pairs, p = 6 × 10^-5, Wilcoxson signed-rank test.

(C) Distribution of residual correlations (after projecting out PM1) in Crus I/II (cyan, n = 16, N = 5) and Lob IV/V (magenta, n = 5, N = 4).

(D) Dependence of residual correlation on distance between GoCs, for positively (red; Pos) and negatively (blue; Neg) correlated pairs (significant compared to each pair’s shuffle distribution) and all pairs (black). Dotted lines with circles represent binned averages (20 μm bins), shaded areas indicate SEMs, and solid lines denote exponential fits to data.

(E) Distribution of distance between GoCs for positively (red) and negatively (blue) correlated pairs and all pairs (black), for 20 bootstrapped samples. Shaded region shows means ± SEMs.

See also Figures S3 and S5.