Table 1.
Dosimetry of dose distribution for accelerated partial breast irradiation, taking into account the parameters of mean dose, Dmax, V5, and V20 in OAR (heart and lungs).
| First Author | Year | Number of Patients | Target | Total Dose [Gy] | Delivery Technique | OAR | Mean Dose | Dmax | V5 | V20 |
|---|---|---|---|---|---|---|---|---|---|---|
| Taghian [26] | 2006 | 25 | APBI | 32 | 3DCPT | Heart | 0 | - | 0.00% | 0.00% |
| Lungs | - | - | 3.00% | 1.00% | ||||||
| Kozak [27] | 2006 | 24 | APBI | 32 | 3DCPT | Heart | 0.1 | - | 0.00% | 0.00% |
| Left Lung | 0.5 | - | 3.00% | 1.00% | ||||||
| Toscas [28] | 2010 | 14 | APBI, deep-seated tumors | 16 | IMPT | Heart | 0.01 | - | 0.00% | - |
| Left Lung | 0.2 | - | V3:1.80% | V10:0.20% | ||||||
| Right Lung | 0.01 | - | V3:0.00% | - | ||||||
| Wang [29] | 2013 | 11 | APBI | 38.5 | PSPB | Heart | - | 3.2 | - | - |
| Lungs | 0.61 | - | 3.50% | 0.10% | ||||||
| Galland-Girodet [30] | 2014 | 19 | APBI | 32 | PSPB | Heart | 0 | 3.8 | 0.40% | 0% |
| Lungs | 0.5 | 20.4 | 3.10% | 0.70% | ||||||
| Hansen [31] | 2015 | 12 | APBI, breast cancer treated with SAVI | 34 | PSPB | Heart | 0.0 | 0.43% | - | - |
| Left Lung | 0.04 | 34.41% | - | - |
OAR—organ at risk; Dmax—maximum dose; V5—the volume of organ receiving 5 Gy; V20—the volume of organ receiving 20 Gy; APBI—accelerated partial breast irradiation; 3DCPT—three-dimensional conformal proton therapy; IMPT—intensity modulated proton therapy; PSPB—passive scattering proton beam; SAVI—Strut-Adjusted Volume Implant.