Table 1.
Different types of dietary fibre cause differential changes to the gut microbiota and metabolic status.
| Author | Study Design | (n) | Study Population | Age (Years) | Duration (Weeks) | Fibre Type | Dose (g/day) | Microbiota | Metabolic Marker |
|---|---|---|---|---|---|---|---|---|---|
| Venktaraman, 2016 [45] | Fibre | 20 | Healthy | 19–20 | 3 | RS2 | 24 | ↑ Ruminococcus bromii, Bifiodbacterium adolescentis | ↑ Butyrate |
| Zhang, 2019 [48] | Randomized, Double-Blind | 19 | Healthy | 18–55 | 4 | RS2 | 40 | ↑ Ruminococcaceae_UCG-005 ↓ Coprococcus, Bacteroides | ↓ Body Fat (%), LDL ↑ GLP-1, Acetate |
| Benítez-Páez, 2019 [50] | Randomized Crossover | 30 | Obese | 36–52 | 4 | Arabinoxylan | 10 | ↑ Prevotella | ↑ SCFA |
| Lu, 2004 [144] | Randomized Crossover | 15 | T2D | 30–74 | 5 | Arabinoxylan | 15 | Not measured | ↓ Fasting glucose and insulin |
| Nicolucci, 2017 [163] | Double-Blind, Placebo | 22 | Obese | 7–12 | 16 | Inulin | 10 | ↑ Bifidobacterium | ↓ Body Weight, Body Fat (%), TAG |
| Ramirez-Faris, 2008 [57] | Randomized, Crossover | 12 | Healthy | 30–64 | 3 | Inulin | 5 | ↑Faecalibacterium prausnitzii | Not measured |
| Wang, 2016 [66] | Randomized, Crossover | 30 | Metabolic Syndrome | 27–78 | 5 | ß-glucan | 5 | ↑ Bacteroides, Prevotella ↓ Dorea | ↓ Total Cholesterol |
| Mitsou, 2010 [69] | Randomized, Double-Blind, Placebo | 52 | Healthy | 39–70 | 4 | ß-glucan | 1 | ↑ Bfidobacterium, ↓ Bacteroides | No significant change |
| Lappi, 2013 [85] | Randomized, Parallel | 52 | Metabolic Syndrome | 40–65 | 12 | Rye | 75 | ↑ Collinsella, Clostridium XIV Bacteroides | No significant change |
| Lee, 2016 [184] | Randomized, Crossover | Healthy | 18–60 | Rye | 40 | Not measured | ↓ Postprandial Glucose and Insulin | ||
| Vitaglione, 2015 [63] | Randomized, Parallel, Placebo | 80 | Obese | 19–67 | 8 | Wheat | 70 | ↑ Firmicutes, Bacteroidetes ↓ Clostridium | No significant change |
| Dall’Alba, 2013 [151] | Randomized, Parallel | 44 | T2D | 32–75 | 6 | Gum guar | 10 | Not measured | ↓ Waist Circumference, HbA1c, TAG |