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. 2021 May 12;12:621007. doi: 10.3389/fimmu.2021.621007

Table 1.

Comparison of visual signs of rejected versus non-rejected transplanted RPE.

Rejection No Rejection
Fundoscopy Clumping of pigment
Optic nerve head hyperemia
Expanding, flat, pigmented layer
OCT Inflammation: CME, choroidal thickening, vitreous haze
Subretinal deposits
Neuroretina atrophy
Disintegration or clumping of transplant material
Hyperreflective monolayer
Healthy neuroretina morphology:
  • -Intact external limiting membrane

  • -Outer nuclear layer > 20 um

FA Optic nerve head leakage
Leakage around graft
Absence of leakage around graft or optic nerve head
AF Uneven autofluorescence
Loss of autofluorescence over time
Double thickness of autofluorescence (transplanted over host RPE)