Table 1.

Mitochondrial redox state biomarkers exhibiting core-rim difference in individual mESC colonies.

	Core			Rim			Core/rim ratio
Sample (#a)	NADH redox ratio	NADH (μM)	Fp (μM)	NADH redox ratio	NADH (μM)	Fp (μM)	Rredox ratio	RNADH	$R_{{\text{F}}_{\text{P}}}$
1 (6)	0.47 ± 0.07	462 ± 89	543 ± 65	0.29 ± 0.03	218 ± 53	510 ± 88	1.64	2.11	1.07
2 (6)	0.35 ± 0.02	201 ± 17	376 ± 26	0.29 ± 0.03	130 ± 23	302 ± 25	1.22	1.54	1.25
3 (16)	0.55 ± 0.04	493 ± 77	431 ± 89	0.42 ± 0.04	250 ± 53	314 ± 66	1.31	1.97	1.37
4 (8)	0.54 ± 0.04	138 ± 22	124 ± 28	0.43 ± 0.02	81 ± 12	95 ± 20	1.26	1.71	1.31
Mean	0.47 ± 0.09	323 ± 180	369 ± 177	0.35 ± 0.07	170 ± 78	305 ± 170	1.36 ± 0.19	1.83 ± 0.26	1.25 ± 0.13
p value	0.02b								0.04c

^aThe number of the analyzed colonies of the corresponding sample.

^bComparison of the mean values of NADH redox ratio between core and rim using two-tailed, paired Student t-test.

^cComparison of the mean values of R_NADH and $R_{{\text{F}}_{\text{P}}}$ using two-tailed, paired Student t-test.