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. 2021 May 14;11(5):730. doi: 10.3390/biom11050730

Figure 4.

Figure 4

Diagram summarizing the pathways that cause NADH increase and NAD+ decrease in the diabetic kidneys. Regeneration of NAD+ from NADH by either mitochondrial complex I or lactate dehydrogenase (under hypoxic conditions) is also shown.