Table 2.

Intestinal effective permeability coefficient (P_eff), apparent permeability coefficient (P_app), and percentage of absorption after SPIP (mean ± SD, n = 4) for OLEA and the reference standard naproxen. Reported data are also included.

Compound	Segment	Peff × 10−4 (cm/s) ± SD	Papp × 10−4 (cm/s) ± SD	Absorption (%)	Study
OLEA	Ileum	1.83 ± 0.18	0.607 * ± 0.202	48.98 ± 12.27	Current study
Naproxen	Ileum	1.47 ± 0.44	0.19 ± 0.018	43.96 ± 7.58	Current study
		1.17 ± 0.23			[57]
		1.78 ± 0.52			[56]
	Jejunum	1.17 ± 0.23			[58]
		1.19 ± 0.12			[33]
		1.47 ± 0.25			[56]
		2.10 ± 0.41			[59]
	Colon	2.06 ± 1.04			[56]

* p < 0.05 differences OLEA vs. naproxen (Mann–Whitney U test).