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. 2021 Apr 12;6(15):10196–10206. doi: 10.1021/acsomega.1c00505

Figure 5.

Figure 5

Piezo1 downregulation affects ESCC cell proliferation, cell cycle progression, and apoptosis. Proliferation was suppressed by Piezo1 downregulation in (a) EC109 cells and (b) EC9706 cells, *** p < 0.001 vs control. (c) Cell cycle distribution of transfected EC109 cells. (d) Analysis of cell cycle distribution in panel C, * p < 0.05 vs control. (e) Cell cycle distribution of transfected EC109 cells. (f) Analysis of cell cycle distribution in panel E, * p < 0.05 vs control. Apoptosis of transfected (g) EC109 cells and (h) EC109 cells. (i) Protein expressions of cleaved-caspase3 and caspase3 in transfected EC109 and EC9706 cells, respectively.