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. 2021 Apr 12;6(15):10196–10206. doi: 10.1021/acsomega.1c00505

Figure 6.

Figure 6

Interaction between p53 and Piezo1, and the protein expression of p53 and Bax. (a) Co-IP between Piezo1 and p53 in EC109 and EC9706 cells. Cell lysates underwent IP using control IgG or the indicated antibody, and the precipitated protein was detected using immunoblotting analysis with the indicated antibody. Cell extracts were used as a positive control (input). (b) Relative mRNA levels of p53 and Bax in transfected EC109 and EC9706 cells, respectively. ** p < 0.01 vs control and * p < 0.05 vs control. (c) Protein expressions of p53 and Bax in transfected EC109 and EC9706 cells, respectively. (d) Relative mRNA expression levels of Piezo1 and p53 in EC109 and (e) EC9706 cell lines after the addition of the p53 inhibitor.