Figure 5.
(A) H&E staining of major tissue and tumor taken from MCF-7/DOXFluc tumor-bearing nude mice after different treatments (200×). Scale bar = 200 μm. (B) Blood biochemical indicators of tumor-bearing nude mice after different treatments. DOX (5 mg/kg, i.v.) and Ber (10 mg/kg, i.p.). * P < 0.05 vs the PBS group. (C) Distribution of DOX in tumor tissue treated by DOX alone or in combination with Ber after 0.5, 2, and 4 h. Significant differences were assessed using the t test. Results are presented as means ± SD.