Table 1. MS-Identified 2D Gel Protein Spots.

	a			b			pI		approx. MW (KDa)
Sr., No.	protein name/ID	accession number	spot number	fold changeb	p-value	FDR	observed	database	observed	database	mascot score	sequence coverage (%)	mass values searched	mass values matched	PMF score
1	vimentin/VIM	P08670	C12/T12	1.51	0.005	0.04	5.12–5.63	5.06	51–54	53.61	73	24	62	11	100.6
2	tubulin beta 2Cchain/TBB2C	P68371	C13/T13	2.50	0.001	0.03	4.63–4.94	4.79	50	50.25	58	40	127	19	145
3	tubulin betachain/TBB5	P07437	C14/T14	–1.13	0.42	0.44	4.47–4.83	4.78	45–49	49.63	90	33	68	11	122
4	tubulin alpha 1Cchain/TBA1C	Q9BQE3	C15/T15	1.54	0.015	0.05	4.87–5.21	4.96	33–36	49.86	76	31	55	9	121
5	actin, cytoplasmic 1/ACTB	P60709	C16/T16	1.57	0.032	0.06	5.1–5.4	5.29	41–45	41.71	157	46	113	12	89.9
6	actin, cytoplasmic 2/ACTG	P63261	C17/T17	1.50	0.014	0.05	5.0–5.5	5.31	43	42.10	76	58	154	17	85.4
7	galectin-1/LGALS1	P09382	C18/T18	1.43	0.034	0.06	5.1–5.3	5.34	8–12	15.04	63	51	74	6	35.8
8	endoplasmin/ENPL	P14625	C19/T19	1.55	0.069	0.10	4.6–4.9	4.76	76–80	92.41	64	33	176	27	135.8
9	retinol-binding protein 1/RBP1	P09455	C20/T20	2.02	0.041	0.07	4.9	4.99	14–16	16.01	62	51	38	8	109
10	albumin, partial/AEE	F6KPG5	C21/T21	–1.72	0.024	0.06	6.7–7.1	5.73	66–71	66.48	72	33	64	16	100.3
11	alloalbumin venezia/AAA	P02768	C22/T22	1.52	0.012	0.05	6.6–6.9	5.99	71	71.17	124	32	74	20	89.7
12	serum albumin/ALBU	P02768	C23/T23	–1.55	0.033	0.06	6.4–6.8	5.92	71	71.31	68	22	75	15	65.6
13	apolipoprotein A-I/APOA1	P02647	C24/T24	–1.74	0.014	0.05	4.3–5.2	5.56	27–32	30.75	77	47%	132	13	94.2
14	collagen alpha 2(VI) chain/COL6A2	P12110	C25/T25	1.56	0.013	0.05	5.6–5.9	5.85	120	108	180	13	41	13	149
15	ATP synthase subunit beta, mitochondrial/ATPB	P06576	C26/T26	2.23	0.034	0.06	4.8–5.1	5.26	45–50	56.52	100	58	160	25	178
16	prohibitin/PHB	P35232	C27/T27	1.26	0.287	0.33	6.2–6.4	5.57	17–20	29.78	62	33	27	6	72
17	phosphatidylethanolamine-binding protein 1/ PEBP1	P30086	C28/T28	–1.29	0.239	0.28	7.1	7.01	17	21.15	61	40	109	8	55
18	keratin 1/K1	H6VRF9	C29/T29	1.42	0.12	0.16	7.2–7.8	7.60	53	66.02	74	25	50	9	84.5
19	keratin, type II cytoskeletal 2 epidermal/K22E	P35908	C30/T30	–1.31	0.14	0.19	8.8	8.07	52–54	65.39	58	22	53	9	81
20	keratin, type I cytoskeletal 9/K1C9	P35527	C31/T31	1.85	0.14	0.18	5.6	5.14	57–62	62.02	69	25	100	13	98

^aSix proteins with fold change ≥1.5, FDR ≤ 0.05, and PMF score >79 are shown in bold.

^b“–” sign denotes downregulated expression in OC.